ASSOCIATION OF VIROLOGICAL BREAKTHROUGH AND CLINICAL OUTCOMES IN ENTECAVIR-TREATED HBEAG-POSITIVE CHRONIC HEPATITIS B.

Association of virological breakthrough and clinical outcomes in entecavir-treated HBeAg-positive chronic hepatitis B.

Background & aimsTo evaluate virological breakthrough (VBT) and the risk of hepatocellular carcinoma (HCC) in HBeAg-positive chronic hepatitis B (CHB) patients receiving entecavir (ETV) treatment.MethodsA retrospective cohort study was conducted in a tertiary referral hospital and a total of 228 HBeAg-positive CHB patients treated with ETV for more

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Ultrasensitive detection of lipoarabinomannan with plasmonic grating biosensors in clinical samples of HIV negative patients with tuberculosis.

BACKGROUND:Timely diagnosis of tuberculosis disease is critical for positive patient outcomes, yet potentially millions go undiagnosed or unreported each year.Sputum is widely used as the testing input, but limited by its complexity, heterogeneity, and sourcing problems.Finding methods to interrogate noninvasive, non-sputum clinical specimens is in

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